Vichaiyut Hospital is the first private general hospital in Bangkok that is not run by a religious organization. Officially opened on June 9, 1969, the medical establishment initially had only ten inpatient beds, five examination rooms, an Operating Room, and a Delivery Room. It was jointly founded by seven physiciansDr. Sermsakdi Phenjati (Obstetrician), Dr. Boonket Laovanich (Surgeon), Dr. Asawin Thepakam (Otolaryngologist), Dr. Sompone Punyagupta (Internist), Dr. Dr. Pradit Chareonthaitawee (Anaesthesiologist), Dr. Chaowalit Preeyasombat (Pediatrician), and Dr. Thamrongrat Keokarn (Orthopaedist)

with Mr. Rangsi Rattanaprakarn as the managing director. Dr. Sompone Punyagupta, who extended his support with the piece of land and funding for the establishment and construction, named this medical establishment Vichaiyut Clinic after the late landlord Lt. Gen. Phra Vichaiyut Dechakanee.

Nine years later, the capital was raised to 20 million baht, and a new entity Vichaiyut Co., Ltd. was registered in 1979. The second hospital building was then constructed with 50 additional inpatient beds, increasing the total to 60. The name of the establishment was also changed to Vichaiyut Hospital. All thanks to the supports from physicians who joined the investment and the treatment force at a later stage, and especially the patients and their relatives who subscribed to the new shares. In addition, the hospital received lots of support in form of money and other donations from its shareholders: Mr. Sirichai Bulkul extended interest-free loan of five million baht in time of tight liquidity; Ms. Jamnien Samerasut donated one ambulance; Mr. Korn and Madam Niramol Suriyasat donated refrigerators and television sets to be installed in every patient rooms; etc.

The number of patients kept rising and the hospital kept adhered to its motto "Quality Medical Service, which has built satisfaction and confidence in the standard of care and treatment. The strengthened foothold and the spread reputation soon led to the necessity for next expansion. In 1996, the hospital further increased its capital by 1,150 million baht. A 21-storey building, Vichaiyut North Tower, was then built, which increased the number of inpatient beds to 350 totally.

And in 2004, a 23-storey "Vichaiyut Medical Center" tower was constructed about opposite to the first building on Setsiri Road. This Medical Center tower has a utility space of 57,000 sq.m., available parking for 500 cars, and a heliport on the 23rd floor. The Vichaiyut Medical Center emphasizes on being the hospitals out-patient center with specialized clinics, over 75 examination rooms, and ambulatory care. It also includes 100 new inpatient rooms and a conference room that can accommodate 1,000 participants for events of the hospital itself and the medical circle.

Vichaiyut Hospital stands firm on the policy of high standard and high quality treatment. The hospital organizes meetings for physicians and nurses on a monthly basis, such as the Journal Club and Mortality Conference, as well as conference on complicated or study cases which are supervised and followed up by team of executive physicians and specialists. Other events hosted by the hospital include Pharmacy Committee , Hospital Quality Committee, conference on infectious diseases in cooperation with Ramathibodi Hospital, and seminar on Gastro-Intestinal diseases in association with the Gastro-Intestinal Association of Thailand.

Vichaiyut Hospital is one of the major institutions accredited by the Medical Council of Thailand and Thailand Nursing Council as an associate institution for continuing education for physicians and nurses. Participants at continuing education programs organized by the hospital are therefore officially acknowledged. The annual 3-day medical conference held at Vichaiyut is participated by physicians from other hospitals nationwide. The hospital also hosts national symposium for nurses.

At Vichaiyut Hospital, the internationally-experienced medical team of over 200 physicians from all medical specialties works closely with over one thousand supporting staff members. Highly acclaimed for its medical ethics, the hospital on November 22, 1994 requested for the royal permission to use the Garuda emblem. The royal permission from H.M. The King was granted on May 24, 2004, which make Vichaiyut the first and the only private hospital so far to receive this honor. Hence, the hospital is regarded as a company of H.M. The King, whose greatness inspires all physicians, nurses and staff members at Vichaiyut to adhere to the high medical standard and healthcare ethics.